Her first line expresses, perhaps, how this woman approaches life.
MISATO:“A desperate effort is better than waiting for a miracle!”
UrsusArctos: Mitsuishi's performance leads me to believe that she was cast as Juri Arisugawa in Revolutionary Girl Utena on the basis of this scene. Juri has the same attitude towards miracles as Misato.
She delivers her second line sternly! And with resolution! (But not shouting)